This Mexican Chicken with Cheese Sauce is the kind of dinner that delivers maximum flavor with minimal effort—just the way we like it on busy weeknights! The juicy, boldly seasoned grilled chicken gets a spicy kick from a smoky blend of spices, and then it’s drenched in a luxuriously creamy cheddar cheese sauce that’s basically liquid gold. It’s quick, comforting, and guaranteed to be a hit at the table.

Why You’ll Love This Recipe

Quick Weeknight Hero: From seasoning to serving, the whole meal comes together in about 35 minutes. Perfect for those nights when you want something homemade without spending forever in the kitchen.
Bold, Spicy Flavors: This dish doesn’t shy away from seasoning. Every bite of the chicken is smoky, zesty, and loaded with Mexican-inspired spices.
Creamy Cheese Sauce Heaven: That cheddar cheese sauce? It’s silky, rich, and adds the perfect cooling balance to the spicy grilled chicken.
Versatile and Crowd-Pleasing: Whether you’re feeding picky eaters or spice lovers, this dish is super easy to customize.

Ingredients You’ll Need

Mexican Chicken with Cheese Sauce Recipe

Let’s break down the stars of the show and why they matter:

For the Chicken:

Chicken Breasts: Boneless and skinless—perfect for grilling and soaking up flavor. You can also use thighs if you prefer darker meat.
Chili Powder: Adds smoky depth and that classic Tex-Mex flavor.
Garlic Powder + Onion Powder: Foundational for building savory flavor—don’t skip these.
Crushed Red Pepper Flakes: Brings a little heat. Adjust to your spice preference.
Dried Oregano: A nice herbal note that balances out the smokiness.
Paprika: For a rich color and mellow, sweet heat.
Ground Cumin: Earthy and warm—key to authentic Mexican flavor.
Salt + Black Pepper: Essential for bringing everything to life.

For the Cheese Sauce:

Butter + Flour: The classic roux base for a creamy, lump-free sauce.
Milk: Helps create the perfect sauce consistency. Whole milk works best for richness.
Extra Sharp Cheddar Cheese: Bold and melty. The sharper, the better—it really cuts through the spices.
Cayenne Pepper: Just a touch for a subtle kick.
Paprika: Adds a warm, smoky edge to the creamy sauce.
Salt: Season to taste, especially since cheese can vary in saltiness.

Variations

Make this recipe your own! Here are a few easy ways to switch things up:

Use Chicken Thighs: Thighs stay juicier and pack even more flavor on the grill.
Make it a Bowl: Serve the chicken and cheese sauce over rice or quinoa with black beans and corn for a full meal.
Add Veggies: Grilled bell peppers, onions, or zucchini are great on the side—or tucked right under the cheese sauce.
Try a Spicy Cheese: Swap sharp cheddar for pepper jack or add diced jalapeños to the sauce for extra fire.

How to Make Mexican Chicken with Cheese Sauce

Step 1: Season the Chicken

Combine all the spices in a bowl and rub generously over both sides of the chicken breasts. Don’t hold back—this rub is where the flavor magic begins.

Step 2: Grill the Chicken

Preheat your grill (or grill pan) over medium-high heat. Cook the chicken for 6–8 minutes on each side, or until the internal temp hits 165°F. Once done, let it rest while you make the sauce.

Step 3: Start the Cheese Sauce

In a saucepan, melt the butter over medium heat. Whisk in the flour and stir until it forms a paste and starts bubbling—this is your roux.

Step 4: Add the Milk

Slowly pour in the milk while whisking constantly. This keeps the sauce smooth. Cook until it’s hot and thickened slightly, but don’t let it boil.

Step 5: Melt the Cheese

Lower the heat and gradually whisk in the shredded cheddar cheese until the sauce is velvety smooth. Stir in paprika, cayenne, and a pinch of salt to taste.

Step 6: Plate and Serve

Slice the grilled chicken and pour that luscious cheese sauce right over the top. Serve hot and enjoy every creamy, spicy bite!

Pro Tips for Making the Recipe

Use a Meat Thermometer: It’s the best way to make sure your chicken is perfectly cooked—no guessing.
Shred Your Own Cheese: Pre-shredded cheese can make the sauce grainy. For the best texture, grate it fresh.
Warm the Milk Slightly: Helps the sauce come together faster and smoother.
Let the Chicken Rest: A few minutes of resting time after grilling keeps the juices locked in.

How to Serve

This dish is super versatile, so here are a few delicious ways to enjoy it:

Classic Plate:

Serve the chicken with a side of Mexican rice, refried beans, or roasted corn. A handful of chopped cilantro or sliced jalapeños on top is chef’s kiss.

Tacos or Wraps:

Slice the chicken and wrap it in warm tortillas with a drizzle of the cheese sauce, some shredded lettuce, and a squeeze of lime.

Low-Carb Option:

Serve it over a bed of cauliflower rice or a green salad for a lighter but still satisfying meal.

Make Ahead and Storage

Storing Leftovers

Keep any leftovers in an airtight container in the fridge for up to 3 days. Store the chicken and sauce separately, if possible.

Freezing

Grilled chicken freezes beautifully! Wrap tightly and freeze for up to 2 months. The cheese sauce, however, is best made fresh, as it can separate when thawed.

Reheating

Reheat the chicken in a skillet or microwave until warmed through. For the sauce, warm it slowly over low heat and whisk in a splash of milk to bring it back to life.

FAQs

Can I make this dish without a grill?
Absolutely! A grill pan or even a regular skillet works just fine. You can also bake the chicken at 400°F for 20-25 minutes if you prefer.

Is this dish very spicy?
It has a mild to moderate heat. If you’re sensitive to spice, reduce or omit the red pepper flakes and cayenne. Want more heat? Add diced jalapeños or use a spicier cheese.

Can I make the cheese sauce ahead of time?
Yes, but it’s best fresh. If you do make it ahead, store it in an airtight container and reheat gently on the stove with a splash of milk to keep it smooth.

What sides go well with this?
Mexican rice, black beans, grilled veggies, or a fresh corn salad all pair beautifully. Even a simple green salad with lime vinaigrette works well.

Final Thoughts

This Mexican Chicken with Cheese Sauce is the ultimate answer to “What’s for dinner?” on a weeknight. It’s packed with smoky, spicy, cheesy flavor and couldn’t be easier to pull together. Try it once, and it just might become your new go-to!